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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HNF4A
All Species:
24.24
Human Site:
T139
Identified Species:
44.44
UniProt:
P41235
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41235
NP_849180.1
474
52785
T139
N
E
R
D
R
I
S
T
R
R
S
S
Y
E
D
Chimpanzee
Pan troglodytes
XP_514664
468
51900
R143
K
E
A
V
Q
N
E
R
D
R
I
S
T
R
R
Rhesus Macaque
Macaca mulatta
XP_001110097
452
49945
S139
Y
E
D
S
S
L
P
S
I
N
A
L
L
Q
A
Dog
Lupus familis
XP_852731
474
52640
T139
N
E
R
D
R
I
S
T
R
R
S
S
Y
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P49698
474
52665
T139
N
E
R
D
R
I
S
T
R
R
S
S
Y
E
D
Rat
Rattus norvegicus
P22449
474
52693
T139
N
E
R
D
R
I
S
T
R
R
S
S
Y
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507309
419
46844
K126
K
C
F
R
A
G
M
K
K
E
A
V
Q
N
E
Chicken
Gallus gallus
NP_001026026
454
50607
T130
N
E
R
D
R
I
S
T
R
R
S
S
Y
E
D
Frog
Xenopus laevis
Q91766
464
51948
T139
N
E
R
D
R
I
S
T
R
R
S
S
Y
E
D
Zebra Danio
Brachydanio rerio
A2T929
430
47452
V131
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49866
666
71882
D189
S
C
R
R
T
S
N
D
D
P
D
P
G
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44960
369
41820
K75
K
C
Q
V
D
K
A
K
R
N
S
C
R
K
C
Sea Urchin
Strong. purpuratus
XP_780389
468
51669
H130
P
Q
L
V
N
A
E
H
M
S
R
Q
V
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.6
90.9
98.3
N.A.
95.7
96.1
N.A.
79.5
84.1
80.8
33.7
N.A.
42.4
N.A.
33.9
57.1
Protein Similarity:
100
82.9
91.9
99.1
N.A.
97
97.4
N.A.
84.8
89.8
89.6
51.4
N.A.
54.5
N.A.
49.5
72.3
P-Site Identity:
100
20
6.6
100
N.A.
100
100
N.A.
0
100
100
6.6
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
26.6
33.3
100
N.A.
100
100
N.A.
20
100
100
26.6
N.A.
20
N.A.
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
8
0
0
0
16
0
0
0
8
% A
% Cys:
0
24
0
0
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
0
0
8
47
8
0
0
8
16
0
16
0
0
0
47
% D
% Glu:
0
62
0
0
0
0
16
0
0
8
0
0
0
47
8
% E
% Phe:
0
0
16
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
8
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
47
0
0
8
0
8
0
0
8
0
% I
% Lys:
31
0
0
0
8
8
0
16
8
8
0
0
0
8
0
% K
% Leu:
0
0
8
0
0
8
0
0
0
0
0
16
8
0
0
% L
% Met:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
47
0
0
0
8
8
8
0
0
16
0
0
0
16
0
% N
% Pro:
8
0
0
0
0
0
8
0
0
8
0
8
0
0
8
% P
% Gln:
0
8
8
0
8
0
0
0
0
0
0
8
8
8
0
% Q
% Arg:
0
0
54
16
47
8
0
8
62
54
8
0
8
8
8
% R
% Ser:
8
0
0
8
8
8
47
8
0
8
54
54
0
0
0
% S
% Thr:
0
0
0
0
8
0
8
47
0
0
0
0
16
0
8
% T
% Val:
0
0
0
24
0
0
0
8
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
47
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _